Overview

• Grey's Anatomy premiered on March 27, 2005, and remains in production, currently airing its 21st season.
• The show became the longest-running primetime medical drama in U.S. history in 2019, surpassing ER.
• Ellen Pompeo, who played Meredith Grey, stepped back from her lead role after season 19 but has returned in a limited capacity.
• The series is celebrated for its innovative storytelling, including song-based episode titles and addressing social issues like domestic violence and reproductive rights.
• Grey's Anatomy has been a platform for nurturing talent, with cast members like Ellen Pompeo and Kevin McKidd making their directorial debuts on the show.