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Global Liver Cancer Cases Could Nearly Double by 2050

The report highlights critical hepatitis B vaccine gaps fueling a rise in preventable liver cancer.

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Scanner d'un foie au CHU de Montpellier, le 7 avril 2015.
Les cancers dus à l’alcool et à l’obésité devraient inéluctablement augmenter dans les prochaines années.
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Overview

  • The Lancet commission projects annual liver cancer cases to reach 1.52 million and deaths to hit 1.37 million by 2050 absent expanded prevention.
  • About 60% of liver cancers are linked to modifiable risks such as viral hepatitis, alcohol misuse and non-alcoholic fatty liver disease.
  • Hepatitis B immunization coverage remains low in Africa and other resource-limited regions, undermining primary prevention efforts.
  • Non-alcoholic fatty liver disease is expected to account for 11% of cases by 2050, up from 8% in 2022, reflecting growing obesity-driven risks.
  • China is forecast to represent roughly 40% of global liver cancer cases due to its high hepatitis B prevalence, highlighting stark regional disparities.