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Global Liver Cancer Burden Could Surge 76% by 2050, Lancet Commission Warns

By 2050, annual new cases may top 1.52 million with 1.37 million deaths if preventable risk factors go unaddressed.

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Leberkrebs ist eine der am schwierigsten zu behandelnden Krebserkrankungen.
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Die weltweite Zahl der Leberkrebs-Fälle wird sich laut einer Studie bis 2050 verdoppeln, wenn nicht mehr gegen vermeidbare Ursachen wie Fettleibigkeit, übermäßiger Alkoholkonsum und Hepatitis unternommen wird.

Overview

  • New analysis forecasts liver cell cancer incidence rising from 870,000 cases in 2022 to 1.52 million in 2050 and annual deaths increasing from 760,000 to 1.37 million.
  • Asia will continue to account for over 70% of global cases while Africa faces the fastest relative growth of about 145% and Europe sees more moderate increases of around 30% in incidence and 36% in mortality.
  • Contributions from hepatitis B and C are projected to decline slightly by mid-century even as alcoholic fatty liver disease rises from 19% to 21% and non-alcoholic fatty liver disease from 8% to 11% of cases.
  • The commission urges expanded hepatitis B vaccination, universal adult hepatitis C testing, alcohol price hikes and warning labels, advertising bans, and regular liver screening for high-risk populations.
  • Liver cancer remains one of the deadliest cancers, with global five-year survival rates between 5% and 30% and a roughly 17% survival rate in Germany, where about 5,700 liver cell cancer cases are diagnosed annually.