Overview

• One death was averted for every 5,400 vaccine doses administered worldwide.
• The study shows 82% of lives saved were among people vaccinated before virus exposure.
• Fifty-seven percent of the total lives saved occurred during the Omicron period, reflecting continued vaccine effectiveness against emerging strains.
• People aged 60 and older accounted for 90% of lives saved and 76% of life-years gained, whereas long-term care residents represented just 2% of those benefits.
• Authors recommend risk-prioritized vaccination campaigns that focus on older and high-risk groups to maximize life-saving potential in future outbreaks.