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Gilead’s Kite to Buy Interius for $350 Million, Adding In‑Vivo CAR T Platform

Kite moves to bring in‑vivo CAR T delivery in-house to cut treatment complexity.

Gilead logo is seen in this illustration taken August 5, 2025. REUTERS/Dado Ruvic/Illustration
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Overview

  • Kite Pharma, a Gilead unit, agreed to acquire privately held Interius BioTherapeutics for $350 million in cash.
  • Interius’ in‑vivo approach delivers DNA by intravenous infusion to program cells inside the patient, aiming to simplify and lower the cost of CAR T therapy.
  • The transaction is expected to close pending regulatory approvals, after which Interius will be integrated into Kite’s research team in Philadelphia.
  • Gilead said the deal will reduce its 2025 earnings per share by approximately $0.23 to $0.25.
  • Investor and clinical interest in in‑vivo CAR T has been rising, with more than $2 billion invested and several programs entering trials, according to Novotech.