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Germany Rolls Out Donanemab for Early Alzheimer’s Patients

Tight criteria with mandatory MRI checks limit access to a small subset of patients.

Overview

  • Eli Lilly said Kisunla is now available in Germany following recent EU authorization.
  • RWTH Aachen expects to start treating eligible patients within one to two weeks.
  • Clinical trials reported a slowing of decline over 18 months, amounting to about four to six months’ benefit.
  • Donanemab is given by infusion every four weeks and must be initiated by physicians experienced in Alzheimer diagnostics with MRI access.
  • Experts estimate fewer than 12,000 people in Germany will qualify due to genetic and anticoagulant exclusions, and they warn of a higher risk of brain edema or microbleeds than with lecanemab, with lower efficacy observed in women.