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Genomic Study Finds Inbreeding Depression in Michigan’s Eastern Massasauga

Habitat fragmentation has isolated populations so severely that pedigree analysis now shows inbreeding depression among rattlesnakes

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Overview

  • A 15-year collaborative field study reconstructed pedigrees for more than 1,000 Eastern Massasauga rattlesnakes across Michigan wetlands
  • The most inbred snakes were about 13% less likely to produce surviving offspring and had nearly a 12% lower annual survival rate compared to less related individuals
  • Roads, farms and development have fragmented wetland habitats, isolating populations and elevating inbreeding risk
  • Researchers used PIT tagging, morphometric measurements and whole-genome sequencing to directly measure fitness effects in a wild venomous species
  • Study authors recommend restoring habitat connectivity and trialing managed translocations to increase gene flow and reduce inbreeding depression