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Genome Study Confirms Potato’s Origin in Ancient Tomato Hybridization

Published July 31 in Cell, the research shows how inherited SP6A and IT1 genes sparked tuber formation, laying the groundwork for restoring ancestral diversity through targeted breeding.

Overview

  • A Cell paper dated July 31 shows that modern potatoes emerged nearly nine million years ago from natural hybridization between ancestral tomato and tuberless Etuberosum lineages.
  • Analysis of more than 450 cultivated and 56 wild potato genomes reveals a balanced mosaic of genetic contributions, including the tuber-initiating SP6A gene from tomato and the stem-growth IT1 gene from Etuberosum.
  • This ancient cross coincided with the rapid uplift of the Andes Mountains, enabling early potato ancestors to survive harsh highland climates through underground nutrient storage and asexual reproduction.
  • Around 20,000 years ago, Indigenous Andean communities domesticated wild potato species, and 16th-century Spanish introduction facilitated their spread into Europe and eventual global adoption.
  • Researchers now aim to harness wild gene pools by reintroducing ancestral alleles into cultivated varieties to expand genetic diversity and strengthen climate resilience in potato breeding programs.