Genetic Link Between Starch Digestion and Dental Health Uncovered

Cornell study finds AMY1 gene variations shape oral bacteria and influence cavity and gum disease risk.

The AMY1 gene, which varies in copy number among individuals, determines how efficiently salivary amylase breaks down starch in the mouth.
Research reveals that individuals with more AMY1 copies have distinct oral bacterial profiles, potentially increasing their risk of cavities and gum disease.
Starch consumption reduces bacterial diversity in the mouth, with certain harmful bacteria less abundant in those with higher AMY1 copy numbers.
The study suggests that genetic variations could lead to personalized dental care, with tailored hygiene and dietary recommendations based on AMY1 copy numbers.
This research highlights the evolutionary role of starch digestion genes, which became more prevalent following the agricultural revolution.