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Genes and Auditory-Reward Disconnect Underlie Musical Anhedonia, Study Finds

A Trends in Cognitive Sciences review traces genetic causes alongside neural mechanisms of musical anhedonia by leveraging fMRI measurements, the Barcelona Music Reward Questionnaire plus twin study data.

Around 10% of people score very low in musical reward sensitivity. (Image by StudyFinds using Shutterstock AI Image Generator)
Why people develop the condition is still unclear, but studies have shown that genetics and environment could both play a role. Credit: Neuroscience News
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Overview

  • People with musical anhedonia experience reduced communication between auditory processing areas and reward networks, as fMRI scans show diminished reward-circuit activation in response to music but normal responses to other stimuli.
  • The Barcelona Music Reward Questionnaire assesses five dimensions of music reward—emotion, mood regulation, social bonding, movement and novelty—and helps quantify individual differences.
  • A twin study suggests genetic factors account for up to 54 percent of the variability in how much pleasure people derive from music.
  • Ongoing collaborations with geneticists aim to identify specific genes linked to musical anhedonia and to determine whether the condition remains stable over the lifespan or can be reversed.
  • The research reframes reward processing as stimulus-specific and raises the possibility of discovering other forms of specific anhedonia across different sensory domains.