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Gene variant may explain asymptomatic COVID-19 cases

  • A common gene variant, HLA-B*15:01, is associated with a higher likelihood of asymptomatic COVID-19 infection.
  • The variant allows the immune system to recognize and respond effectively to SARS-CoV-2 before symptoms develop.
  • People with the gene variant were over twice as likely to have an asymptomatic infection compared to the general population.
  • The findings could inform the development of new vaccines and therapies tailored to this immune response.
  • More diverse research is needed to fully understand the role of genetics in different populations and outcomes.
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