Gene TRPC5 Identified as Key to Obesity and Postnatal Depression

Researchers discover that the TRPC5 gene affects oxytocin neurons, offering potential new treatments for these conditions.

TRPC5 gene disruption leads to obesity, anxiety, and postnatal depression in both humans and mice.
The gene affects oxytocin neurons in the hypothalamus, crucial for regulating appetite and emotions.
Restoring TRPC5 function in animal models reduced weight and alleviated depressive symptoms.
Oxytocin treatments show promise for managing symptoms linked to TRPC5 deficiencies.
Findings may pave the way for new diagnostic markers and therapeutic strategies.