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Gene Therapy Shows Dramatic Vision Restoration in Rare Eye Condition

Patients with Leber congenital amaurosis experience significant improvements in vision following innovative treatment.

Subjects who received higher doses saw greater improvements in their vision. Credit: Neuroscience News
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Overview

  • Clinical trial participants saw up to a 10,000-fold increase in light sensitivity.
  • The therapy, ATSN-101, was injected under the retina and tested in varying doses.
  • Significant improvements in reading and navigation abilities were noted.
  • Most side effects were minor and related to the surgical procedure.
  • Further trials are planned to confirm safety and efficacy for broader use.