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Gene Hackman’s Final Autopsy Confirms Heart Disease and Alzheimer’s as Causes of Death

The actor’s autopsy also revealed prolonged fasting, while his wife Betsy Arakawa succumbed to hantavirus pulmonary syndrome in their rodent-infested Santa Fe home.

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Gene Hackman attends the premiere of the film "The Royal Tenenbaums" December 6, 2001 in Hollywood, CA. (Photo by Vince Bucci/Getty Images)
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Overview

  • Gene Hackman, 95, died from severe cardiovascular disease with advanced Alzheimer’s as a contributing factor, confirmed by the final autopsy report released on April 27, 2025.
  • Toxicology reports showed elevated acetone levels in Hackman’s system, indicating prolonged fasting before his death around February 18.
  • Betsy Arakawa, 65, died approximately a week earlier on February 11 from hantavirus pulmonary syndrome, a rare disease linked to rodent exposure.
  • Investigators ruled out carbon monoxide poisoning and hantavirus as causes of Hackman’s death, confirming no signs of foul play or external trauma.
  • The couple’s home was found in disrepair, with widespread rodent infestation contributing to Arakawa’s hantavirus exposure, as confirmed by health officials.