Overview

• In a randomized controlled trial, postmenopausal women who added an average of 25 daily sit-to-stand transitions saw a 2.24 mmHg drop in diastolic blood pressure over three months.
• The group instructed to sit less cut daily sedentary time by 75 minutes but did not achieve statistically significant improvements in blood pressure.
• Neither the sit-less nor sit-to-stand intervention produced meaningful changes in blood sugar, indicating the trial’s cardiovascular effects were independent of metabolic shifts.
• Publication in Circulation offers a clear, actionable strategy to translate broad public health advice on sitting less into achievable daily habits.
• The research team has applied for NIH funding to extend the trial’s duration and include older men and women to validate and expand on these cardiovascular benefits.