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France Puts Three Regions on Pre‑Epidemic Flu Alert as Vaccinations Top 8.3 Million

European surveillance points to an early season linked to an evolving H3N2 sub‑clade, prompting appeals to eligible people to vaccinate now.

Overview

  • Pharmacies have sold more than 8.3 million flu vaccine doses since October 14, about 22% higher than the same point in 2024 and equal to roughly 43.7% of the 19 million people targeted.
  • Santé publique France lists Île‑de‑France, Normandie and Nouvelle‑Aquitaine in a pre‑epidemic phase, with Mayotte already in an epidemic, as influenza A activity increases, particularly among children.
  • The ECDC says flu cases are appearing three to four weeks earlier than recent seasons across Europe and urges eligible people to get vaccinated without delay.
  • Scientists are monitoring an H3N2 “sub‑clade K” that could raise transmissibility and allow partial immune escape, though vaccination remains the best defense against severe illness.
  • The Health Ministry calls the early uptake encouraging but stresses it is too soon to judge the campaign’s success; more than half of early vaccinations were administered by pharmacists, while bronchiolitis is expanding and COVID‑19 indicators are declining.