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Flu Surge Accelerates as H3N2 'Subclade K' Drives Early Season Across U.S.

Vaccines still blunt severe disease despite a partial mismatch to the fast-spreading H3N2 K variant.

Overview

  • The CDC estimates 4.6 million illnesses, 49,000 hospitalizations and 1,900 deaths so far this season, including three children.
  • About 90% of subtyped influenza A viruses are H3N2 subclade K, and hospitalizations rose about 14% week over week with multiple states at high or very high activity levels.
  • Connecticut reports a December spike in flu hospitalizations, and New York City logged 24,607 lab-confirmed cases by Dec. 13.
  • Early U.K. analyses indicate reduced protection against infection in adults (roughly 32–39%) but stronger protection against hospitalization in children (around 72–75%).
  • Health authorities urge vaccination for everyone 6 months and older, prompt antivirals for high‑risk patients, and precautions such as staying home when sick and using masks in crowded indoor spaces.