Particle.news

Download on the App Store

First Shunt Candida Auris Brain Infection Cured as UK Designates It Notifiable and Researchers Unveil Promising Drugs

The breakthrough comes as UK health authorities require mandatory reporting of all C. auris cases.

Overview

  • A 34-year-old patient in the UAE became the first person to have an external ventricular shunt C. auris infection cleared without intrathecal treatment following a traumatic brain injury.
  • Clinicians employed a three-phase antifungal regimen—injectable therapy, IV drips and oral tablets—that eradicated the fungus and enabled discharge after a seven-month hospital stay.
  • UK Health Security Agency has classified Candida auris as a notifiable infection, mandating all confirmed cases be reported to strengthen outbreak monitoring and control.
  • King’s College London scientists led by Professors Miraz Rahman and Mark Sutton reported preclinical azole derivatives that penetrate fungal cells, disrupt biofilms and protect animal models without toxic effects.
  • Candida auris, identified in 2009 and now detected in over 40 countries, persists on surfaces and skin, has a 30–60% fatality rate and its growing resistance is linked to widespread antifungal overuse.