First Potential HIV Cure Reported in France Following Bone Marrow Transplant

A woman in Marseille is the first in France and eighth worldwide to achieve HIV remission after receiving a transplant from a donor with a rare genetic mutation.

A French woman, diagnosed with HIV in 1999, has shown no detectable virus since stopping antiretroviral treatment in October 2023.
Her remission follows a 2020 bone marrow transplant to treat acute myeloid leukemia, using a donor with the CCR5 Delta32 genetic mutation that blocks HIV entry into cells.
This case marks the eighth reported instance of HIV remission worldwide through this method, with the first case documented in Berlin in 2009.
Doctors emphasize that this approach is not a generalizable treatment due to the risks and complexity of bone marrow transplants, which are typically reserved for severe conditions like leukemia or lymphoma.
The case offers new avenues for HIV research but requires long-term monitoring to confirm the durability of the results.