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First Human Death from Shamonda Virus Confirmed in Lyon

Authorities say a probable Culicoides midge bite infected a severely immunocompromised patient, triggering multidisciplinary One Health investigations.

Overview

  • French ministries confirmed on October 22 that tests identified the Shamonda virus in a patient who died in early October after care at the Hospices civils de Lyon.
  • The patient was severely immunocompromised and was being treated for a serious illness when neurological complications that investigators now link to Shamonda were observed before death.
  • Officials say the working hypothesis is a vector-borne spillover from a Culicoides biting midge in eastern France, where the virus circulated in livestock in spring and summer 2026.
  • Clinical, laboratory and epidemiological investigations are ongoing with human, animal and environmental experts and authorities state that no public-health risk to the general population has been identified at this time.
  • Shamonda is an orthobunyavirus known mainly from livestock and first seen in Europe this summer, and the case raises questions about host vulnerability and the need for strengthened One Health surveillance of animals and people.