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First Experimental Proof Reveals Mechanical Cause of Skin Wrinkles

Using a low-force tensometer on skin samples aged 16 to 91, the study shows that inherent pre-stretch coupled with age-driven contraction causes the skin to buckle into wrinkles.

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Overview

  • The study by Guy German’s team at Binghamton University is the first to experimentally validate age-related wrinkle theories with actual human skin samples
  • Using a low-force tensometer to stretch skin strips from donors aged 16 to 91, researchers observed that lateral contraction under tension increases with age, causing buckling
  • Results confirm that skin is inherently pre-stretched, with internal tensile forces driving wrinkle formation as contraction intensifies
  • Chronological aging yields mechanical effects similar to those from chronic sun exposure, producing comparable increases in contraction that lead to buckling
  • Published in the Journal of the Mechanical Behavior of Biomedical Materials, the findings establish a rigorous physical basis for evaluating anti-aging treatments