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First Comprehensive Study Finds Drug-Discovery Potential in Endangered Meghalaya Plant

Peer-reviewed results highlight preclinical signals requiring rigorous validation.

Overview

  • Nagaland University and Assam Down Town University reported the first comprehensive analysis of Goniothalamus simonsii, publishing the findings in the journal Chemistry and Biodiversity.
  • Led by Dr Mayur Mausoom Phukan, the team identified diverse bioactive phytochemicals with antioxidant, antimicrobial, anti-inflammatory, anti-diabetic, and anticancer properties.
  • Laboratory assays showed strong antiproliferative effects of plant extracts against colon cancer cells, indicating early-stage anticancer potential.
  • Computational modeling suggested interactions between the plant’s natural compounds and cancer-related proteins, offering leads for nature-based therapeutics.
  • Researchers emphasized the plant’s endangered status in Meghalaya and its traditional medicinal use, calling for targeted conservation and further safety and efficacy studies.