Overview

• On August 18, 2025, Jasveen Sangha agreed to plead guilty to multiple federal counts, including conspiracy to distribute ketamine and maintaining a drug-involved premises, becoming the last of five defendants in the Matthew Perry overdose investigation to do so.
• With Sangha’s agreement, all principal figures—from Perry’s assistant and intermediaries to prescribing physicians—have now pleaded guilty, and federal prosecutors are scheduling successive sentencing hearings, beginning with Dr. Salvador Plasencia on December 3, 2025.
• Prosecutors have relied on transaction records showing large ketamine purchases—such as 25 vials bought four days before Perry’s death—deleted Signal messages and testimony about injections administered by Perry’s assistant as core evidence.
• The case maps a multi-tiered pipeline in which licensed doctors, middlemen and a high-end supplier known as the “Ketamine Queen” diverted large quantities of the anesthetic outside medical channels.
• Prosecutors and medical experts say the proceedings expose weaknesses in oversight of off-label ketamine therapy and underscore the dangers of unregulated drug diversion.