Overview

• The FDA said on Sept. 23 it would require new warning language noting a possible association between prenatal acetaminophen use and neurodevelopmental outcomes.
• President Trump urged people not to use Tylenol, including during pregnancy and in children, prompting confusion and heightened scrutiny of the science.
• WHO stated there is no conclusive evidence that acetaminophen in pregnancy causes autism, and ACOG and the AAP reaffirmed guidance for judicious, clinician‑guided use.
• Recent large observational studies, including Swedish and Japanese cohorts, reported negligible or no meaningful differences in autism diagnoses linked to prenatal exposure.
• Clinicians and commentators warn that alarmist claims could deter needed treatment or push parents toward aspirin for fevers, reviving concerns about Reye syndrome.