Fantasy Football Week 14: Key Sleepers and Injury Updates

With six teams on bye in a pivotal week, fantasy managers face tough lineup decisions and must rely on emerging players like Isaac Guerendo to secure playoff spots.

Week 14 marks one of the most significant bye weeks of the season, with six teams sidelined, including fantasy-relevant stars like Lamar Jackson, Derrick Henry, and Jonathan Taylor.
Isaac Guerendo steps into the 49ers' lead running back role following injuries to Christian McCaffrey and Jordan Mason, making him a top waiver-wire target against a Bears defense struggling against the run.
Quarterbacks Sam Darnold, Will Levis, and Aidan O'Connell are highlighted as potential sleeper options in favorable matchups for fantasy managers navigating bye week challenges.
Injury updates include Trevor Lawrence placed on injured reserve, Mac Jones taking over as Jaguars quarterback, and key players like CeeDee Lamb and D'Andre Swift dealing with injuries but likely to play.
Defensive matchups to consider include the Saints against the struggling Giants offense and the 49ers facing a Bears team allowing significant points to opposing defenses.