Overview

• At the ESCRS meeting in Copenhagen, researchers reported that 766 presbyopia patients gained an average 3.45 Jaeger lines one hour after the first dose.
• Formulations used fixed diclofenac with 1%, 2% or 3% pilocarpine given twice daily with an optional third dose, and benefits persisted with a median duration of 434 days.
• In the 1% group, 99% read two or more extra lines, while 69% in the 2% group and 84% in the 3% group read three or more lines.
• Side effects were mostly mild—temporary dim vision (32%), irritation (3.7%) and headache (3.8%)—with no discontinuations or serious events reported.
• Independent experts highlighted the retrospective single-center design and urged multi-center, long-term randomized trials and ongoing safety monitoring before broad recommendation.