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Extracellular Vesicles Crucial for Brain Development, Study Finds

New research highlights the role of EVs in cell communication and potential therapeutic applications.

  • Extracellular vesicles (EVs) facilitate specialized communication between different brain cell types during development.
  • EVs carry proteins and transcription factors, such as YAP1, directly to the nucleus of recipient cells, inducing gene changes.
  • The composition of EVs varies among different cell populations and brain regions, suggesting a tightly regulated biogenesis.
  • High-resolution imaging shows EVs entering the nucleus of neural progenitor cells during cell division.
  • These findings could pave the way for new therapeutic approaches to treat neurological diseases.
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