Overview
- Indianapolis enters 3-0 with one of the league's most productive offenses at 418.7 yards per game.
- Los Angeles is 2-1 after a Week 3 loss to the Eagles in which a 19-point lead evaporated.
- A compilation of more than 35 picks from USA TODAY, ESPN, CBS Sports, Sports Illustrated and Bleacher Report largely sides with the Rams.
- The Rams listed five limited participants in Wednesday's practice, including guard Steve Avila returning in a limited capacity and defensive tackle Braden Fiske with an oblique issue.
- The Colts saw DeForest Buckner, Matt Goncalves, Kenny Moore and Alec Pierce miss practice, with their availability to be monitored before kickoff.