Overview

• Regulation (EU) 2025/877, effective 1 September 2025, prohibits the manufacture, import, marketing and sale of cosmetics containing TPO and dimethyl‑p‑toluidine across the EU.
• The compounds, widely used as photoinitiators to cure semipermanent gels and polishes under LED or UV lamps, are now barred from cosmetic formulations.
• The ban stems largely from animal toxicology indicating carcinogenic and reproductive risks, with limited human data supporting a precautionary approach.
• Manufacturers and nail salons must shift to compliant alternatives and withdraw affected products from services, and consumers are urged to check labels for these ingredients.
• Coverage diverges on whether pre‑ban stock can still be used or must be removed, prompting businesses to consult the Official Journal text (DOUE L877/1) and national regulators for enforcement guidance.