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EU Authorizes Zurzuvae, First Drug Specifically for Postpartum Depression

Clinicians gain a faster-acting option subject to pregnancy and breastfeeding restrictions.

Overview

  • The European Commission granted EU-wide approval for Zurzuvae (zuranolone) in September 2025, marking the first authorization targeted specifically at postpartum depression.
  • Clinical studies cited in reporting indicate symptom improvements can appear within about two weeks of treatment.
  • The medicine must not be used during pregnancy and is not recommended during breastfeeding because transfer into breast milk cannot be excluded.
  • Experts and advocates stress the drug expands options but does not replace psychotherapy, social support, or practical postpartum help.
  • Postpartum depression affects an estimated 10–15% of mothers in Europe, and specialists highlight ongoing gaps in recognition and routine screening.