Overview
- The Liga Profesional confirmed Rosario Central vs. Estudiantes for Sunday, November 23 at 17:30 at the Gigante de Arroyito in a single-match tie.
- Estudiantes advanced as the eighth-placed team in Zone A with 21 points after a Banfield draw and unfavorable results for Huracán, Defensa y Justicia and Belgrano preserved its spot.
- Ariel Holan faces his fifth knockout as Central coach with a 2–2 record in previous eliminations after defeating Estudiantes 2–0 in May through goals by Carlos Quintana and Jáminton Campaz.
- Central earned home advantage by winning its group and leading the annual table, while the Clausura knockouts are hosted by higher seeds with extra time and penalties if required.
- Estudiantes will be without Santiago Ascacíbar (suspension for yellow-card accumulation), Guido Carrillo (four-match ban) and Gabriel Neves (muscular injury) for the visit to Rosario.