Engineered Parasite Shows Promise for Treating Neurological Disorders
Scientists explore Toxoplasma gondii's potential to deliver therapeutic proteins across the blood-brain barrier.
- Toxoplasma gondii, a common parasite, can cross the blood-brain barrier, making it a potential vehicle for delivering treatments.
- Researchers have successfully engineered T. gondii to deliver the MeCP2 protein, which could help treat Rett syndrome and other neurological conditions.
- Lab tests on human brain organoids and mice showed that the engineered parasite could deliver proteins with minimal side effects.
- Further research is needed to improve the safety and efficiency of this method before it can be used in humans.
- The study highlights the innovative use of natural organisms to overcome challenges in neurological healthcare.