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Eli Lilly to Acquire Verve Therapeutics as Gene-Editing Trial Begins

The $1.3 billion purchase marks a major step in Lilly’s expansion into PCSK9-targeting therapies with closing slated for Q3 2025.

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Overview

  • Lilly agreed to pay $1.3 billion for Cambridge-based Verve at a 113% premium to its 30-day volume-weighted average trading price.
  • The acquisition remains subject to approval and is expected to complete in the third quarter of 2025.
  • Verve has dosed its first patient with a CRISPR base-editing treatment designed to permanently deactivate the PCSK9 gene and lower LDL cholesterol.
  • Verve’s shares surged roughly 80% on June 17 following the deal announcement and news of its first patient dosing.
  • The deal advances Lilly’s diversification into cardiovascular genetic medicine while its current valuation sits below its three-year average P/E ratio.