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Eli Lilly Picks Huntsville for $6 Billion API Plant to Supply Next-Gen Drugs

The move advances onshoring of active ingredients to support orforglipron within Lilly’s $27 billion U.S. buildout.

Overview

  • Construction is slated to begin in 2026 with completion targeted for 2032, according to the company.
  • Lilly expects about 3,000 construction jobs and roughly 450 permanent roles for engineers, scientists, operations staff and lab technicians.
  • The facility will produce small‑molecule and peptide medicines, including orforglipron, which is under FDA priority review.
  • The Huntsville site was selected from more than 300 proposals, with proximity to the HudsonAlpha Institute cited for workforce training and research ties.
  • It is the third of four new U.S. plants in an at‑least $27 billion expansion, with plans for AI‑enabled, automated operations and progress toward carbon neutrality.