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ECDC Warns of Early Flu Season in Europe as New H3N2 Subclade Spreads

Early analyses suggest adults receive markedly less protection from the current vaccine than children.

Overview

  • The ECDC reports influenza activity is rising across the European Economic Area about three to four weeks earlier than in recent seasons and urges immediate vaccination of at-risk groups.
  • Surveillance identifies A(H3N2) subclade K as the main driver of current transmission across Europe.
  • Genetic differences from the WHO-selected J.2 vaccine strain and early UK data point to a mismatch, with estimated protection of about 70–75% in vaccinated children versus roughly 30–40% in adults against severe disease.
  • The United Kingdom has entered an early wave with increasing hospitalizations and modeling of higher transmissibility, while Germany’s RKI notes only sporadic cases so far, including some A(H3N2).
  • ECDC is preparing for a potentially more severe season though the impact on health systems remains uncertain, and national guidance such as Stiko’s advises high-risk groups to get vaccinated now.