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Early Exposure to 'Forever Chemicals' Linked to Long-Term Gut Health Issues

Penn State study finds early-life exposure to TCDF disrupts gut microbiome, raising risk of metabolic disorders.

  • Research shows that TCDF, a common pollutant, can permanently alter the gut microbiome in mice.
  • Disrupted microbiomes in early life are associated with higher risks of obesity and type 2 diabetes in later life.
  • The study used a dose higher than typical human exposure to identify potential toxicity points.
  • Key gut bacterium Akkermansia muciniphila was significantly reduced in exposed mice.
  • Probiotic treatment restored the gut microbiome in affected mice, suggesting potential for future therapies.
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