Early Exposure to 'Forever Chemicals' Linked to Long-Term Gut Health Issues
Penn State study finds early-life exposure to TCDF disrupts gut microbiome, raising risk of metabolic disorders.
- Research shows that TCDF, a common pollutant, can permanently alter the gut microbiome in mice.
- Disrupted microbiomes in early life are associated with higher risks of obesity and type 2 diabetes in later life.
- The study used a dose higher than typical human exposure to identify potential toxicity points.
- Key gut bacterium Akkermansia muciniphila was significantly reduced in exposed mice.
- Probiotic treatment restored the gut microbiome in affected mice, suggesting potential for future therapies.