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Early Combination Therapy Proven to Reduce Heart Attack Risks

Research confirms that starting statins and ezetimibe within 12 weeks of a heart attack significantly lowers the risk of further cardiovascular events and deaths.

  • A study of 36,000 Swedish heart attack patients (2015–2022) shows early dual therapy with statins and ezetimibe improves outcomes compared to delayed or single-drug treatments.
  • Patients receiving the combination therapy within 12 weeks achieved cholesterol targets faster, reducing risks of recurrent heart attacks, strokes, and death.
  • The findings challenge current stepwise treatment guidelines, which delay achieving cholesterol goals and risk losing patients to follow-up.
  • Ezetimibe, an affordable and widely available drug with minimal side effects, makes early combination therapy cost-effective and accessible globally.
  • Swedish hospitals implementing updated treatment algorithms have seen significant improvements in patient outcomes, prompting calls for global guideline revisions.
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