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Early Cancer Gene Panel Testing Linked to Longer Survival in Kyoto Study

Researchers urge Japan to end its post‑treatment testing rule based on new multicenter outcome data.

Overview

  • Kyoto University Hospital announced on Nov. 28 that conducting genomic panel testing before starting standard therapy was associated with longer survival than testing after completing it.
  • The study tracked 172 patients with unresectable advanced or recurrent gastrointestinal and lung cancers across six domestic centers beginning in 2021 for three years.
  • Actionable alterations were found and recommended targeted therapies were delivered to 43 patients, representing 25% of those tested.
  • Among patients who received panel‑guided treatment, the risk of death was 41% lower compared with other participants, the researchers reported.
  • Lead investigator Professor Manabu Muto said earlier testing enables timely access to effective drugs and called for lifting Japan’s reimbursement limit that confines testing to after standard treatment, a policy in place since 2019.