Overview
- Sportsbooks list Philadelphia around -270 on the money line with a -5.5 spread and a total near 44.5, according to the latest previews.
- San Francisco enters with lineup uncertainty, with Trent Williams and Ricky Pearsall questionable and multiple linebackers also listed as questionable, while reports note Nick Bosa and Fred Warner are already sidelined.
- ESPN betting analysis highlights the Eagles' league-low rate of passing touchdowns allowed under Fangio, informing a pick of Brock Purdy under 1.5 passing TDs.
- Recommended props from ESPN include Christian McCaffrey over 57.5 rushing yards and A.J. Brown over 5.5 receptions, with Saquon Barkley projected for increased involvement.
- The Grandstand backs Jalen Hurts over 207.5 passing yards, citing the 49ers' No. 25 pass defense and forecast conditions that should be serviceable for the passing game.