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Drifted H3N2 Variant Drives Early Flu Surge in England as UKHSA Reports Strong Child Vaccine Protection

Preliminary UKHSA analysis finds this season’s flu vaccine strongly protects children despite the drifted H3N2 variant.

Overview

  • UKHSA says a drifted A(H3N2) subclade known as K now dominates cases in England, with hospital admissions rising earlier than usual to 3.8 per 100,000 from 2.4 the previous week.
  • Early effectiveness estimates show the 2025/26 vaccine prevents 70–75% of hospital attendances in children aged 2–17 and 30–40% in adults, according to UKHSA.
  • The NHS has issued a ‘flu jab SOS’ as uptake lags in vulnerable groups, with reports that about two in five care home residents remain unvaccinated.
  • Paediatric leaders at the RCPCH warn H3N2 can be life‑threatening in rare cases and urge parents to ensure children receive the nasal spray vaccine.
  • Researchers report the circulating H3N2 acquired multiple mutations over the summer; Australia recorded its worst flu season on record and Japan saw epidemic outbreaks and school closures, trends UK officials are watching closely.