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Dopamine Shows Promise in Reducing Alzheimer's Plaques

Japanese researchers find dopamine treatments increase enzyme activity that breaks down harmful brain plaques in mice, offering potential for new therapies.

  • Dopamine boosts neprilysin, an enzyme that degrades beta-amyloid plaques linked to Alzheimer's.
  • L-DOPA treatment in mice led to reduced plaques and improved memory function.
  • Neprilysin levels naturally decrease with age, potentially serving as an early Alzheimer's biomarker.
  • Further research needed to understand dopamine's regulation of neprilysin and manage L-DOPA's side effects.
  • Human trials are required to confirm the effectiveness of dopamine-based treatments for Alzheimer's.
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