Overview
- Novak Djokovic lost to Mariano Navone 7-6(5), 5-7, 4-6, 6-2, 6-1 in a five-set match that ended Sunday night at Arthur Ashe Stadium.
- Djokovic received treatment from tournament medics, took a medical timeout before the fifth set, and repeatedly vomited and cramped during the match as his movement and serve fell away.
- The defeat ended Djokovic's streak of opening-round Grand Slam wins that stretched back to 2006 and halts his bid for a record 25th major.
- Navone, a 25-year-old Argentine ranked outside the top 40, recorded the biggest win of his career and advances to the US Open second round, reshaping Djokovic's section of the draw.
- The result raises immediate questions about Djokovic's fitness and schedule with medical evaluation expected next and potential implications for his short- and long-term playing plans.