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Diet Drinks Linked to Higher Liver Disease Risk and Death, Large UK Analysis Finds

The conference presentation reported observational associations that remain unvetted by peer review.

Overview

  • Using UK Biobank data from 123,788 adults without baseline liver disease, researchers tracked beverage intake over roughly a decade.
  • Sugar‑sweetened beverages were associated with about a 50% higher risk of metabolic dysfunction‑associated steatotic liver disease (MASLD).
  • Low‑ or non‑sugar‑sweetened beverages showed an even stronger link, with about a 60% higher MASLD risk and a higher rate of liver‑related death.
  • Across participants, both drink types correlated with greater liver fat content, and 108 liver‑related deaths were recorded during follow‑up.
  • Study authors advised limiting both beverage types, noting that substituting water was associated with up to a 15% lower liver disease risk.