Overview
- The round-of-16 pairings were drawn on Sunday at the Deutsches Fußballmuseum in Dortmund.
- All eight ties will be played on 2–3 December 2025.
- Borussia Dortmund will host Bayer Leverkusen, while record winners Bayern Munich travel to Union Berlin.
- Defending champions VfB Stuttgart visit 2. Bundesliga side VfL Bochum, with other ties including Mönchengladbach vs. St. Pauli, Hamburg vs. Holstein Kiel, Freiburg vs. Darmstadt, RB Leipzig vs. Magdeburg, and Hertha vs. Kaiserslautern.
- The DFB confirmed the calendar: quarterfinals on 3/4 and 10/11 February 2026, semifinals on 21/22 April, and the final on 23 May at Berlin's Olympiastadion.