Overview

• A June 29 study in Expert Opinion on Drug Safety reported that women using Depo-Provera for more than one year face a 3.5-fold increased risk of intracranial meningiomas compared with combined birth control pills.
• Multidistrict Litigation No. 3140 in the U.S. has expanded to over 550 lawsuits alleging Pfizer failed to warn users about the brain tumor risk linked to Depo-Provera.
• Health authorities in the UK, Europe, Canada and South Africa have mandated updated warnings for long-term use, while the U.S. Food and Drug Administration has not required equivalent label changes.
• An estimated 74 million women worldwide rely on Depo-Provera injections, raising significant public health concerns over the newly confirmed tumor risks.
• Hundreds of women in the UK are considering legal action against Pfizer for not disclosing the elevated meningioma risk associated with the contraceptive injection.