Deep Brain Stimulation Enables Walking in Paralyzed Patients

Researchers have discovered that stimulating the lateral hypothalamus can restore mobility and improve autonomy in individuals with spinal cord injuries.

• Scientists at EPFL and Lausanne University Hospital achieved a breakthrough by applying deep brain stimulation (DBS) to the lateral hypothalamus (LH), a brain region not previously associated with walking.
• Two patients with partial spinal cord injuries regained mobility and independence, with improvements persisting even after the stimulation was turned off.
• The therapy promoted the reorganization of residual nerve fibers, suggesting long-term neurological recovery beyond immediate effects.
• The research relied on advanced brain imaging and precise surgical techniques, with real-time patient feedback confirming the effectiveness of the targeted stimulation.
• Future studies aim to combine DBS with spinal implants to create a comprehensive recovery strategy for spinal cord injury patients.

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