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DBV Peanut Allergy Patch Succeeds in Pivotal Phase 3, Setting Up 2026 FDA Filing

Topline data show a sizable response advantage over placebo with mostly mild skin reactions.

Overview

  • DBV Technologies reported that 46.6% of children aged 4–7 on the Viaskin Peanut patch met responder criteria at 12 months versus 14.8% on placebo.
  • Investigators defined response by increases in eliciting dose measured via double‑blind, placebo‑controlled food challenges.
  • The VITESSE trial enrolled 654 participants, randomizing 438 to active therapy and 216 to placebo, and achieved 96.2% overall compliance.
  • Safety findings were consistent with prior studies, with mainly local skin reactions, no treatment‑related serious adverse events, and treatment‑related anaphylaxis in 0.5% of patients (n=2), both of whom continued therapy.
  • DBV said it plans a U.S. Biologics License Application in the first half of 2026, and shares jumped to a new 52‑week high on the news.