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Dark Chocolate Compound Linked to Lower Biological Age in Human Study

The peer-reviewed analysis links higher blood theobromine to epigenetic clock and telomere estimates, with no proof of causation.

Overview

  • King’s College London researchers reported that people with higher circulating theobromine had lower biological ages in two European cohorts.
  • Biological age was estimated from blood-based DNA methylation clocks and methylation-derived telomere length measures.
  • The association appeared specific to theobromine after tests of other cocoa and coffee metabolites showed no similar links.
  • The study was observational and cross-sectional, so confounding may exist, and the authors advise against eating more dark chocolate given sugar and fat content.
  • The findings were published December 10 in Aging, and the team says more research will probe mechanisms and evaluate whether the link is causal.