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Danish Study Confirms No Link Between Vaccine Aluminum and Childhood Disorders

Findings dispel safety concerns by showing cumulative aluminum exposure from childhood immunizations does not raise risks for chronic autoimmune, allergic or neurodevelopmental conditions.

SEATTLE, WA - JUNE 21: A 20-month-old baby receives the first dose of the Pfizer Covid-19 vaccination at UW Medical Center - Roosevelt on June 21, 2022 in Seattle, Washington. Covid-19 vaccinations for children younger than 5 began today across the U.S. (Photo by David Ryder/Getty Images)
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A baby receives a Prevnar Pneumococcal Meningitis vaccine at Intermed Pediatric Care in South Portland, Maine, on Feb. 5, 2015.
Daniela Chavarriaga holds her daughter, Emma Chavarriaga, as pediatrician Jose Rosa-Olivares, M.D. administers a measles vaccination during a visit to the Miami Children's Hospital on June 2, 2014, in Miami, Florida.

Overview

  • Published July 14 in the Annals of Internal Medicine, the study tracked 1,224,176 Danish children born 1997–2018 using nationwide health registries and Cox proportional hazards models to examine cumulative aluminum exposure.
  • Adjusted hazard ratios per 1 milligram increase in aluminum were 0.98 for autoimmune, 0.99 for atopic or allergic and 0.93 for neurodevelopmental disorders, indicating no moderate risk increases.
  • No statistically significant associations were found for specific conditions including asthma, autism spectrum disorder or ADHD among children receiving higher doses of aluminum-adjuvanted vaccines.
  • External experts hailed the analysis as the largest and most definitive observational study on vaccine aluminum safety and said its robust design addresses earlier flawed research.
  • Researchers emphasized that aluminum salts remain essential adjuvants with no current substitutes and urged parents to rely on this evidence to guide vaccination decisions.