Overview
- The study analyzed 1,224,176 children born between 1997 and 2018, linking vaccination records to national health registries tracking 50 chronic conditions through age five or end of 2020.
- Researchers measured cumulative aluminum exposure before age two and used Cox proportional hazards models to estimate risks for autoimmune, atopic or allergic, and neurodevelopmental outcomes.
- Hazard ratios per additional milligram of aluminum were 0.98 for autoimmune diseases, 0.99 for allergic disorders and 0.93 for neurodevelopmental conditions including autism spectrum disorder and ADHD.
- The research was prompted by a 2022 CDC-funded study that failed to distinguish between aluminum sources and it directly addresses concerns raised by vaccine skeptics.
- Authors say findings affirm the safety of aluminum-adjuvanted vaccines and support their continued role as critical components of childhood immunization programs.