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Danish Nationwide Study Finds No Link Between Vaccine Aluminum and Child Chronic Disorders

Tracking aluminum exposure in early childhood vaccines across Denmark’s registries provides robust reassurance that immunization programs pose no added chronic disorder risk

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A baby receives a Prevnar Pneumococcal Meningitis vaccine at Intermed Pediatric Care in South Portland, Maine, on Feb. 5, 2015.

Overview

  • The study analyzed 1,224,176 children born between 1997 and 2018, linking vaccination records to national health registries tracking 50 chronic conditions through age five or end of 2020.
  • Researchers measured cumulative aluminum exposure before age two and used Cox proportional hazards models to estimate risks for autoimmune, atopic or allergic, and neurodevelopmental outcomes.
  • Hazard ratios per additional milligram of aluminum were 0.98 for autoimmune diseases, 0.99 for allergic disorders and 0.93 for neurodevelopmental conditions including autism spectrum disorder and ADHD.
  • The research was prompted by a 2022 CDC-funded study that failed to distinguish between aluminum sources and it directly addresses concerns raised by vaccine skeptics.
  • Authors say findings affirm the safety of aluminum-adjuvanted vaccines and support their continued role as critical components of childhood immunization programs.